Mark T Dransfield Selected Research

Chronic Bronchitis

11/2023	Pulmonary emphysema subtypes defined by unsupervised machine learning on CT scans.
3/2016	Acquired Cystic Fibrosis Transmembrane Conductance Regulator Dysfunction in Chronic Bronchitis and Other Diseases of Mucus Clearance.
1/2016	Pilot evaluation of ivacaftor for chronic bronchitis.
1/2016	Therapeutic Approaches to Acquired Cystic Fibrosis Transmembrane Conductance Regulator Dysfunction in Chronic Bronchitis.
1/2016	A ferret model of COPD-related chronic bronchitis.
10/2015	A Randomized, Placebo-controlled Trial of Roflumilast. Effect on Proline-Glycine-Proline and Neutrophilic Inflammation in Chronic Obstructive Pulmonary Disease.
6/2014	Predictors of chronic obstructive pulmonary disease exacerbation reduction in response to daily azithromycin therapy.
3/2014	Cystic fibrosis transmembrane conductance regulator activation by roflumilast contributes to therapeutic benefit in chronic bronchitis.
2/2014	Impact of heterozygote CFTR mutations in COPD patients with chronic bronchitis.

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Mark T Dransfield Research Topics

Disease

141	Chronic Obstructive Pulmonary Disease (COPD) 03/2024 - 08/2004
22	Emphysema 11/2023 - 12/2010
13	Inflammation (Inflammations) 01/2019 - 08/2013
11	Dyspnea (Shortness of Breath) 10/2020 - 11/2011
9	Chronic Bronchitis 11/2023 - 02/2014
9	Asthma (Bronchial Asthma) 01/2023 - 06/2011
9	Pneumonia (Pneumonitis) 12/2021 - 03/2008
4	Disease Progression 07/2023 - 12/2013
4	Lung Diseases (Lung Disease) 01/2023 - 01/2012
4	Cardiovascular Diseases (Cardiovascular Disease) 01/2018 - 06/2014
3	Coronary Artery Disease (Coronary Atherosclerosis) 11/2023 - 01/2017
3	Weight Loss (Weight Reduction) 01/2023 - 05/2020
3	Obstructive Lung Diseases (Obstructive Lung Disease) 10/2020 - 01/2019
3	Infections 01/2020 - 01/2018
2	Neoplasms (Cancer) 01/2023 - 11/2022
2	Obesity 01/2023 - 12/2021
2	Pulmonary Emphysema 10/2022 - 12/2018
2	Airway Obstruction (Choking) 10/2021 - 01/2016
2	Anemia 07/2021 - 05/2020
2	Hypoxia (Hypoxemia) 07/2021 - 12/2018
2	Cachexia 05/2020 - 12/2013
2	Lung Injury 11/2018 - 02/2014
2	Cough 01/2016 - 04/2015
2	Cystic Fibrosis (Mucoviscidosis) 01/2016 - 12/2013
2	Pulmonary Hypertension 01/2016 - 04/2014
2	Diphtheria 09/2012 - 09/2009
1	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2024
1	Bronchitis 11/2023
1	Lung Neoplasms (Lung Cancer) 11/2022
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2022
1	Polycythemia (Erythrocytosis) 07/2021
1	Chronic Disease (Chronic Diseases) 10/2020
1	Fatigue 05/2020
1	Anorexia 05/2020
1	Frailty 01/2020

Drug/Important Bio-Agent (IBA)

24	GoldIBA 07/2023 - 11/2011
22	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2023 - 05/2013
20	fluticasone furoate FDA Link 12/2022 - 05/2013
20	vilanterolIBA 12/2022 - 05/2013
17	Biomarkers (Surrogate Marker)IBA 01/2023 - 07/2009
17	Bronchodilator Agents (Bronchodilators)IBA 01/2022 - 08/2004
13	GSK573719IBA 12/2022 - 01/2016
11	SmokeIBA 01/2024 - 06/2006
8	Metoprolol (Toprol-XL)FDA LinkGeneric 11/2023 - 01/2016
8	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 01/2019 - 01/2012
7	Oxygen (Dioxygen)IBA 07/2021 - 01/2004
6	Azithromycin (Zithromax)FDA LinkGeneric 01/2019 - 08/2011
5	RoflumilastIBA 01/2023 - 02/2014
5	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 06/2014
4	CalciumIBA 11/2023 - 12/2010
4	Fibrinogen (Factor I)FDA Link 01/2022 - 01/2016
4	SteroidsIBA 01/2022 - 08/2004
4	Fluticasone-Salmeterol Drug Combination (Advair)FDA Link 09/2014 - 08/2004
3	Immunoglobulin G (IgG)IBA 01/2023 - 09/2009
3	Immunoglobulin E (IgE)IBA 12/2020 - 01/2018
3	C-Reactive ProteinIBA 05/2020 - 01/2016
3	CytokinesIBA 01/2020 - 02/2015
3	Glycine (Aminoacetic Acid)FDA LinkGeneric 11/2019 - 12/2013
3	Proline (L-Proline)FDA Link 11/2019 - 12/2013
3	CollagenIBA 11/2018 - 12/2013
3	Proteins (Proteins, Gene)FDA Link 11/2018 - 09/2009
3	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2018 - 01/2016
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2017 - 06/2011
3	ChloridesIBA 02/2014 - 08/2013
3	Pneumococcal Vaccines (Pneumococcal Polysaccharide Vaccine)IBA 09/2012 - 03/2008
2	CadmiumIBA 01/2024 - 01/2022
2	MucinsIBA 11/2023 - 03/2010
2	AntibodiesIBA 01/2023 - 09/2009
2	Phosphodiesterase 4 InhibitorsIBA 01/2023 - 03/2014
2	Angiotensin Receptor AntagonistsIBA 10/2022 - 10/2021
2	Losartan (Cozaar)FDA LinkGeneric 10/2022 - 10/2021
2	Hemoglobins (Hemoglobin)IBA 07/2021 - 05/2020
2	Heme (Haem)IBA 05/2020 - 11/2018
2	Environmental Pollutants (Pollutants, Environmental)IBA 01/2020 - 10/2013
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 12/2018 - 06/2014
2	GlucocorticoidsIBA 05/2018 - 06/2014
2	Muscarinic AntagonistsIBA 05/2018 - 04/2018
2	Tiotropium Bromide (Spiriva)FDA Link 04/2018 - 02/2016
2	Carbon MonoxideIBA 01/2018 - 07/2013
2	ivacaftorIBA 01/2016 - 01/2012
2	Superoxides (Superoxide)IBA 02/2015 - 06/2011
2	Polysaccharides (Glycans)IBA 09/2012 - 03/2008
2	23-valent pneumococcal capsular polysaccharide vaccineIBA 09/2012 - 09/2009
1	Chloride Channels (Chloride Channel)IBA 01/2024
1	E-Cigarette VaporIBA 01/2023
1	Glycopyrrolate (Glycopyrronium Bromide)FDA LinkGeneric 01/2022
1	indacaterolIBA 01/2022
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 10/2021
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 10/2021
1	AllergensIBA 12/2020
1	IronIBA 05/2020
1	Complement System Proteins (Complement)IBA 01/2020

Therapy/Procedure

44	Therapeutics 01/2024 - 02/2011
10	Nebulizers and Vaporizers (Inhaler) 03/2022 - 04/2018
5	Palliative Care (Palliative Therapy) 03/2024 - 01/2019
3	Ambulatory Care (Outpatient Care) 01/2023 - 04/2015
3	Pneumonectomy (Lung Volume Reduction) 01/2020 - 01/2012
3	Lung Transplantation 01/2018 - 01/2012
2	Patient Readmission 01/2019 - 01/2016
2	Length of Stay 01/2018 - 02/2011